Saturday, July 30, 2016

HR/BUS/GralInt-Climbing Down the Corporate Ladder Without Alarming Your Boss

The following information is used for educational purposes only.

































Climbing Down the Corporate Ladder Without Alarming Your Boss

The Workologist

By ROB WALKER JULY 22, 2016



Send your workplace conundrums to workologist@nytimes.com, including your name and contact information (even if you want it withheld for publication). The Workologist is a guy with well-intentioned opinions, not a professional career adviser. Letters may be edited.


I’ve had a successful career in banking and financial services. Now, however, I want to downsize my role and responsibilities. How do I sell my skills and talents while seeking a more junior role than my career history suggests? I am not looking for part-time work. But, for example, I’d like to be part of a team, rather the leader. JOHN, HOUSTON
This question may seem surprising, given that we are more or less conditioned to believe that work is all about moving up the ladder — or at the very least, never slipping down it. But Jenny Blake has heard stories like this before. She is an author and a career coach who specializes in career shifts, which is the subject of her forthcoming book, “Pivot: The Only Move That Matters Is Your Next One.” (Ms. Blake was a manager at Google before starting her own business. “When I looked ahead to my trajectory, to climb the ranks of management, I realized, ‘I don’t want that at all,’” she said.)
But it is possible that any given boss may take a more traditional view and interpret any attempt by you to “downsize” your responsibilities as an announcement that you’re ready to start coasting toward retirement. So it’s important to frame this carefully.

Start by seeking out others in your company (and in your field) who have made a similar transition, Ms. Blake suggests, and find out how they managed it. And think of this move in positive terms — “going from a more senior position into a more specialized one,” as she put it. “And really examine what individual contributor role you’d find most exciting.” Take this seriously: You want to think about an outcome that you would genuinely feel good about.
Then, when you actually go to management, don’t be apologetic. “Frame it as: ‘I’ve given this some reflection, and the things that I am truly best at, and where I’ve really had the most impact, are X, Y and Z,” Ms. Blake said. Give specific examples — the “categories of impact, and the results in those areas,” she said. The bottom line is sending the message that this isn’t about kicking back; it’s about doing what most excites you, and thus what should excite your employer, in this new, more focused role.
It may also be worth using essentially the same process to explore opportunities elsewhere. (The Workologist is, in general, always a fan of remaining open to opportunities elsewhere.) But you may discover that your current employer is your best bet. Sometimes, Ms. Blake said, it’s actually a relief to management that not everyone is angling for the same outcome; it can be extremely valuable when a skilled employee “moves to a different track” that can help the company in new ways.
Quality Over Quantity in a Job Hunt
Your recent advice to a reader who asked about “résumé optimization” was spot on, but I suspect there is a deeper problem: Applying online to job postings is a terribly inefficient way to look for a job. I have read that 70 percent of job openings are filled by referrals, or by candidates already known to the company — and I suspect the number may be higher. I publishguides and run workshops on career matters, and I always stress the importance of networking as the best strategy for finding work. In fact, I ask job seekers to make me a promise: For every three hours you spend searching and applying online, spend seven hours networking. It pays off. DOUG KALISH, PALO ALTO, CALIF.
I’m happy to receive this comment (and a few others from readers who made related points), because it gives me a reason to expand on something I only had room to hint at in that column. All the experts I talked to cautioned against going overboard with online application processes: While applying for a zillion jobs feels productive, it’s often more effective to take more care in pursuing a smaller number of more thoughtfully targeted positions.
More specifically, one of those sources made a related point that didn’t respond directly to that reader’s specific query, but that I strongly agree with. Jane Horowitz, a career coach and founder of More Than a Résumé, in Denver, says she tells her clients, often young people just entering the job market, that even when you submit a résumé online to a company you really want to work for, that’s only the first step. The second is to find someone you know who can help get that résumé in front of a human being. “Try to find another way into the company,” Ms. Horowitz says. “You have to.”
In other words: Network, person-to-person. This is exactly why the Workologist believes the job search should be a permanent activity, at least on some low-key level. Today’s casual acquaintance could be tomorrow’s crucial link to a new and better gig.
As far as I can determine, that statistic about 70 percent of openings being filled via referrals factors in internal job searches that are never actually listed in public, and is thus a guess, at best. But a 2014 study by researchers from the Federal Reserve and M.I.T., scrutinizing data from one financial services firm, found that 30 to 50 percent of hires came by way of referrals — even though these made up a slender proportion of applicants, particularly compared with the volume of online applicants.
So, yes, your résumé should be “optimized” for applicant-tracking systems. But don’t spend all your energy on that. Taking time to arrange one informational interview that really cements a productive contact who will remember you and your skills, Ms. Horowitz suggested, might well prove to be more supportive.

GralInt-The Power of ‘Why?’ and ‘What If?’

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The Power of ‘Why?’ and ‘What If?’


Preoccupations


By WARREN BERGER JULY 2, 2016


Recently I had a conversation with a chief executive who expressed concern about several of her senior managers. They were smart, experienced, competent. So what was the problem? “They’re not asking enough questions,” she said.
This wouldn’t have been a bad thing in the business world of a few years ago, where the rules for success were: Know your job, do your work, and if a problem arises, solve it and don’t bother us with a lot of questions.
But increasingly I’m finding that business leaders want the people working around them to be more curious, more cognizant of what they don’t know, and more inquisitive — about everything, including “Why am I doing my job the way I do it?” and “How might our company find new opportunities?”
I may be hyper-aware of this trend because I think of myself as a “questionologist,” having studied the art of questioning and written a book about it. But I also think there are real forces in business today that are causing people to value curiosity and inquiry more than in the past.
Companies in many industries today must contend with rapid change and rising uncertainty. In such conditions, even a well-established company cannot rest on its expertise; there is pressure to keep learning what’s new and anticipating what’s next. It’s hard to do any of that without asking questions.
Steve Quatrano, a member of the Right Question Institute, a nonprofit research group, explains that the act of formulating questions enables us “to organize our thinking around what we don’t know.” This makes questioning a good skill to hone in dynamic times.
Asking questions can help spark the innovative ideas that many companies hunger for these days. In the research for my book, I studied business breakthroughs — including the invention of the Polaroid instant camera and the Nest thermostat and the genesis of start-ups like Netflix, Square and Airbnb — and found that in each case, some curious soul looked at a current problem and asked insightful questions about why that problem existed and how it might be tackled.
The Polaroid story is my favorite: The inspiration for the instant camera sprang from a question asked in the mid-1940s by the 3-year-old daughter of its inventor, Edwin H. Land. She was impatient to see a photo her father had just snapped, and when he tried to explain that the film had to be processed first, she wondered aloud, “Why do we have to wait for the picture?”
One might assume that people can easily ask such questions, given that children do it so well. But research shows that question-asking peaks at age 4 or 5 and then steadily drops off, as children pass through school (where answers are often more valued than questions) and mature into adults. By the time we’re in the workplace, many of us have gotten out of the habit of asking fundamental questions about what’s going on around us. And some people worry that asking questions at work reveals ignorance or may be seen as slowing things down.
So how can companies encourage people to ask more questions? There are simple ways to train people to become more comfortable and proficient at it. For example, question formulation exercises can be used as a substitute for conventional brainstorming sessions. The idea is to put a problem or challenge in front of a group of people and instead of asking for ideas, instruct participants to generate as many relevant questions as they can. Kristi Schaffner, an executive at Microsoft, regularly conducts such exercises there and says they sharpen analytical skills.
Getting employees to ask more questions is the easy part; getting management to respond well to those questions can be harder. When leaders claim they want “everyone to ask more questions,” I sometimes (in my bolder moments) ask: “Do you really want that? And what will you do with those questions once people start asking them?”

For questioning to thrive in a company, management must find ways to reward the behavior — if only by acknowledging the good questions that have been asked. For example, I visited one company that asked all employees to think of “what if” and “how might we” questions about the company’s goals and plans. Management and employees together decided which of these mission questions were best, then displayed them on banners on the walls.
Leaders can also encourage companywide questioning by being more curious and inquisitive themselves. This is not necessarily easy for senior executives, who are used to being the ones with the answers. I’ve noticed during questioning exercises at some companies that top executives sit in the back of the room, laptops open, attending to other business; they seem to think their employees are the only ones who need to learn. As they do this, these leaders are modeling precisely the kind of incurious behavior they’re trying to change in others.
They could set a better example by asking “why” and “what if” — while asking others to do likewise. And as the questions proliferate, some good answers are likely to follow.


WARREN BERGER is the author of “A More Beautiful Question” (Bloomsbury USA).

GralInt-Graduating and Looking for Your Passion? Just Be Patient

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Graduating and Looking for Your Passion? Just Be Patient


Preoccupations

By ANGELA DUCKWORTH JUNE 4, 2016


For all their grandeur and euphoria, graduation ceremonies can be harrowing. Until that momentous day, you’re a student whose job is to do what your teacher asks. Now you have to ask things of yourself — but what?
If you’re relying on a commencement speaker to set your compass, you may still be confused at day’s end. In my experience, it’s common to hear “Follow your passion” from the podium. This is great counsel if, in fact, you know what that passion is. But what if you don’t?
Young graduates might imagine that discovering your passion happens the way it does in a movie: with a flash of insight and a trumpet blast. Before that flash, you were struggling to find yourself, and in the next moment, you know exactly who you were meant to be.
As a psychologist who studies world-class achievers, I can say the reality of following your passion is not very romantic. It takes time to develop a direction that feels so in-the-bones right that you never want to veer from it.
Thus, my advice to young graduates is not to “follow your passion” but rather, to “foster your passion.” Here are three suggestions for doing so.

Move toward what interests you.

Don’t panic if you can’t think of a career path that’s a perfect fit. In large part, this is because interests are not just discovered, they’re developed. Scientists have learned that the sort of enduring fascination that commencement speakers like to praise usually takes time and experience to bloom fully.
For instance, when she graduated from Smith College, Julia Child had no idea that she would fall in love with French cuisine in her late 30s. She had no inkling that writing cookbooks and teaching on television would one day become her calling.
A good-enough fit is a more reasonable aim than a perfect one. Consider your first job as an opportunity to begin an unpredictable, inefficient trial-and-error process. The violist Roberto Díaz told me he didn’t know he’d love the viola before he tried it, and his tepid reaction to the violin could not have foretold the lifelong love affair he has had with the ever-so-slightly-larger viola.
As I said to one young man who, on the cusp of his first real job, was paralyzed by indecision: “Don’t overthink it. Move in the direction of something that feels better than worse.”

Seek purpose.

People are hard-wired not only to gratify their personal desires but also tocare for others. So rather than ask, “What do I want to be when I grow up?” ask, “In what way do I wish the world were different? What problem can I help solve?” This puts the focus where it should be — on how you can serve other people.
Analyzing data I’ve collected on thousands of American adults, I’ve found that those who have an enduring passion answer affirmatively to statements like, “In choosing what to do, I always take into account whether it will benefit other people” and “I have a responsibility to make the world a better place.”
Once you’ve thought of what or whom you care about most, write it down. Psychologists have found that asking people to reflect in writing on their core values has miraculous effects on motivation. Because these are often the values you will be remembered for — what David Brooks calls “eulogy virtues” — you might consider writing a paragraph about what you would like people to say about you after you’ve drawn your last breath. It sounds grim, but perhaps the perspective will help you figure out what to do while you have the time to do it.

Self-oriented motives like interest and other-oriented motives like altruism are not mutually exclusive. In fact, personal interest and self-transcendent purpose are the dual engines of intrinsic motivation. In combination, they’re more powerful than alone. In one study, municipal firefighters who expressed interest in their work and concern for the welfare of the public averaged more than 50 percent more overtime hours than others.
Speaking for myself, psychology attracts my attention more than any other topic, but what gets me out of bed in the morning isn’t just curiosity. I enjoy my work, and at the same time I believe that doing it well can contribute to the well-being of other people.

Finish strong.

Your first job is unlikely to be your last. Once you figure out your next step, what should you do?
I confess it took a fair bit of job swapping before I knew that psychological research would become my long-term career. But in each of those jobs, I picked up knowledge and skills that I was able to weave into my current work.
Also consider the commitment you made when you accepted a job. Did you pledge to stay for a year? Did you promise two weeks’ notice before leaving? Try to keep your word. While personal growth is important, it is imperative to act like the professional adult you are.
Work as hard on your last day as on your first. No matter where you go next, you have an opportunity to make the most of where you are now.



Angela Duckworth is the founder and scientific director of Character Lab and the author of “Grit: The Power of Passion and Perseverance” (Scribner).

BUSWRIT/GralInt-10 Common Business Writing Mistakes

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Top 10 Common Business Writing Blunders & 5 Everyday Grammatical Mistakes (Infographic)
Source: www.grammarcheck.net

Thursday, July 28, 2016

GralInt-Toms Founder Blake Mycoskie Explains The New One For One Marketplace

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Toms Founder Blake Mycoskie Explains The New One For One Marketplace


TechCrunch


Published on Nov 21, 2013


TOMS founder Blake Mycoskie has only just gotten started on his mission and with the launch this month of a new e-commerce initiative called TOMS Marketplace, the one-for-one concept that's been popularized by TOMS is moving well beyond shoes and sunglasses. Colleen Taylor talks with Founder of Toms, Blake Mycoskie.

Subscribe to TechCrunch today: http://bit.ly/18J0X2e

TechCrunch is a leading technology media property, dedicated to obsessively profiling startups, reviewing new Internet products, and breaking tech news.





































Source:www.youtube.com



GralInt-Blake Mycoskie, TOMS - Conscious Capitalism and the Future of Business

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Blake Mycoskie, TOMS - Conscious Capitalism and the Future of Business


Credit Suisse


Published on Apr 11, 2014


Blake Mycoskie, Founder of TOMS and best-selling author, discusses how to succeed with a mission-driven business model.

Credit Suisse hosted its fifth annual Entrepreneurs Summit at the Sundance Resort in Utah, returning to a place famed for its rocky peaks, snow-covered forests and emphasis on creativity and innovation. In line with the theme "Turning Ideas into Action," a select group of 60 entrepreneurs and innovators engaged in wide-ranging discussions on strategies and best practices that allow entrepreneurs to transform and revolutionize industries. In hosting this annual Summit, Credit Suisse aims to support entrepreneurs at every stage of their business growth to forge new partnerships, inspire new ideas, and foster a community of leading entrepreneurs.



































Source:www.youtube.com



GralInt-"Responsible Capitalism and the Future of Business" -Tij Innova 12-

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"Responsible Capitalism and the Future of Business" -Tij Innova 12-


Published on Oct 20, 2012


Oct 20, 2012 by MgCrOl: Keynote by Blake Mycoskie -Entrepreneur philanthropist, owner of Tom shoes, popular around the world and one of the most interesting conferences of the day.

"Capitalismo consciente y el futuro de los negocios". Tijuana Innovadora 2012











































Source: www.youtube.com

GralInt-Blake Mycoskie, shares his lessons in leadership.

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Blake Mycoskie, shares his lessons in leadership.




Published on Aug 25, 2015



We profile Blake Mycoskie, founder of TOMS, and find out about his leadership style, what makes his company successful & why he believes to give is to live.

































Source:www.youtube.com

GralInt-The Pool meets Blake Mycoskie, founder of TOMS

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The Pool meets Blake Mycoskie, founder of TOMS

The Pool UK



Published on May 28, 2015


Fashion Director Stacey Duguid went to talk ethical business, fatherhood, and the reason he started TOMS






































Source: www.youtube.com

GralInt-How TOMS Founder Blake Mycoskie Crafted an Intentional Brand | Inc. Magazine

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How TOMS Founder Blake Mycoskie Crafted an Intentional Brand | Inc. Magazine



Published on Nov 12, 2014



Blake Mycoskie, the founder of TOMS, talks to Inc.'s Scott Gerber about starting a mission-based business, the challenges of manufacturing globally, and how he learned-- the hard way--that shoes are best sold in boxes, not bags.

Subscribe to Inc.'s channel, click here: http://www.youtube.com/user/incmagazi...

Click here to watch part 2 - TOMS founder Blake Mycoskie: How to Create More Jobs in the U.S. http://www.inc.com/blake-mycoskie/how...

Facebook: https://www.facebook.com/Inc
Twitter: https://twitter.com/Inc
G+: https://plus.google.com/+incmagazine/...
Linkedin: https://www.linkedin.com/company/inc....






































Source: www.youtube.com

GralInt-TOMS & the Future of the One for One Movement (Full Session) | Interactive 2014 | SXSW

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TOMS & the Future of the One for One Movement (Full Session) | Interactive 2014 | SXSW



Published on Apr 16, 2014


Founder of TOMS, Blake Mycoskie, believes that "doing it different" is as important to success as "doing good." This belief has caught on across the business sector and continues to make a huge impact on the world. At SXSW Blake will share how placing a relentless focus on being disruptive by disregarding traditional business wisdom is the only way to take your idea to the next level.

Honoring this belief through his own work, Blake will unveil the next product of the One for One® movement and explain why pushing limits and taking more risks is more important than ever before. With the next chapter, TOMS moves beyond accessories and evolves into an everyday experience seeking to improve lives each day.

Attend this session to be the first to experience the future of One for One!





































Source: www.youtube.com









CHANGE/MANAG/GralInt-Kotter's 8 Steps/Lesson 8 Applying Kotter's 8 Step Change Model

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Kotter's 8 Steps


Published on Jun 23, 2015

Change model by John Kotter (1996)





















































Lesson 8 Applying Kotter's 8 Step Change Model

Teo Hiro


Published on May 5, 2016


Business: Principles of Management

Ch 5. Organizational Change

Lesson 8 Applying Kotter's 8-Step Change Model

Instructor: Sherri Hartzell



Sherri has taught college business and communication courses. She also holds three degrees including communications, business, educational leadership/technology.
John Kotter's 8-step change model is widely accepted across all industries as an effective model for implementing organizational change. In this lesson, each step of the Kotter model is discussed using Carl's carwash as the contextual example for making lasting change at the carwash.
Reviewing Kotter's 8-Step Model
When attempting to implement transformational change in organizations many managers will turn to the work of John Kotter as a guide. If you recall, John Kotter's change model includes eight steps, including: establish a sense of urgency, create a guiding coalition, develop a vision and strategy, communicate the change vision, empower broad-based action, generate short-term wins, consolidate gains to produce more change and anchor change in the organizational culture.
In this lesson, each step of the Kotter model is discussed using Carl's carwash as the contextual example for making lasting change at the carwash.
Applying Kotter's 8-Step Model
Carl is an owner of a local carwash that has struggled to maintain a steady flow of customers in the past months. The reasons for this change range from a poor economy to the recent building of two franchisecarwash locations within ten miles of Carl's carwash. Carl knows that if he does not do something quick to change the current status of his carwash, he will soon be out of business.
After much deliberation and brainstorming, Carl has decided to introduce an interior shampooing service to the menu of services the carwash offers. The goal is to generate additional revenue and maintain a competitive advantage over other carwashes in the area. From past experience, Carl understands how important it is to use a change model to guide the process of implementing this new service. He turns to Kotter's eight steps.
Establishing a Sense of Urgency
To establish a sense of urgency Carl holds a meeting with his staff to discuss the current financial situation at the carwash. He informs his employees that they are all on the verge of losing their jobs due to the limited revenue coming into the carwash. Carl assures his employees that closing the doors to the carwash is the last thing he wants to do, but that it is a reality they are all facing. He explains the need for change at the carwash and shows the connection between making changes and creating job security for his employees. Carl's employees recognize their jobs as being in jeopardy and express their commitment to making whatever changes are necessary to secure the longevity of their jobs and the carwash.
Creating the Guiding Coalition
Now that Carl's employees understand the sense of urgency of the change, he must decide who his guiding coalition will be. This step will require Carl to select employees who will help him to see the change through. Carl chooses five employees: Maria to help with the logistics of acquiring the necessary equipment for the shampooing service; Jose and Mark to learn the process of shampooing, and who will be tasked with training other employees on how to perform the shampooing service; Samantha for marketing the new service; and Adam to work on pricing of the new service. These five employees form the guiding coalition who will provide the necessary direction for developing and implementing the new shampooing service at the carwash.
Creating and Communicating a Vision for Change
Carl must now think about how he will present this change to the rest of the employees. Creating a change vision will allow Carl to provide his employees with a clear understanding of what the change is all about. He must create a vision that connects the new shampoo service to long-term sustainability of the carwash. Once this vision is written, Carl must communicate the vision to his entire staff. Carl's employees will need to know what's in it for them. Therefore, Carl will need to show not only the connection between the new shampoo service and the long-term sustainability of the carwash, but also how the long-term sustainability of the carwash will lead to the long-term security of their jobs.
Empowering Broad-Based Action
For the new shampooing service to be successfully developed and implemented, Carl also knows he needs to spend time identifying and removing potential barriers to efficiency to empower broad-based action in his employees and the guiding coalition. Carl must make sure that his employees have all of the resources they need to accomplish their respective tasks in the change process. He must also make sure the carwash has adequate staff to begin offering this new service and the means to promote the service to new and existing customers.



















Source: www.youtube.com

MANAG/GralInt-McKinsey on Change Management

The following information is used for educational purposes only.






McKinsey on Change Management




Published on May 20, 2014


































Source: www.youtube.com



MANAG/GralInt-Change Management explained in 1 minute!

The following information is used for educational purposes only.





Change Management explained in 1 minute!

Doodle Slide


Published on Mar 16, 2012











































Source:www.youtube.com










































Source: http://changeactivation.com/simplechangeguide#.V5pCPrjhCM8

MANAG/GralInt-How to Lead Change Management

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How to Lead Change Management


Published on Jun 9, 2014


DeAnne Aguirre, senior partner with Strategy&, discusses techniques that can help companies transform quickly and effectively. For more insights, read "10 Principles of Leading Change Management": strategy-business.com/ChangeManagement.
































Source: www.youtube.com






LEAD/MANAG/GralInt-Change Management vs. Change Leadership — What's the Difference?

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Change Management vs. Change Leadership — What's the Difference?


Published on Feb 6, 2012

John Kotter discusses the difference between "change management" and "change leadership," and whether it's just a matter of semantics. These terms are not interchangeable. The distinction between the two is actually quite significant. Change management, which is the term most everyone uses, refers to a set of basic tools or structures intended to keep any change effort under control. The goal is often to minimize the distractions and impacts of the change. Change leadership, on the other hand, concerns the driving forces, visions and processes that fuel large-scale transformation. In this video, I delve a little deeper into the differences between the two concepts, and highlight why we need more change leadership today.
































Source: www.youtube.com

LEAD/MANAG/GralInt-TED Talks-Lead and be the change: Mark Mueller-Eberstein at TEDxRainier

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Lead and be the change: Mark Mueller-Eberstein at TEDxRainier


Published on Dec 11, 2012

Professor Mark Mueller-Eberstein is an internationally acclaimed business leader, entrepreneur, consultant, researcher, best-selling author, and teaches at the Rutgers University Center for Management Development. Mark explores the dynamic between the human and technical factors that positively impact business operations and how businesses can leverage key technology trends.

This talk was given at TEDxRainier in Seattle on November 10, 2012. In the spirit of ideas worth spreading, TEDx is a program of local, self-organized events that bring people together to share a TED-like experience. At a TEDx event, TEDTalks video and live speakers combine to spark deep discussion and connection in a small group. These local, self-organized events are branded TEDx, where x = independently organized TED event. The TED Conference provides general guidance for the TEDx program, but individual TEDx events are self-organized.* (*Subject to certain rules and regulations)




























Source: www.youtube.com




SALUD/HEALTH/GralInt-Hepatitis, una enfermedad silenciosa: cómo evitar su contagio

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Hepatitis, una enfermedad silenciosa: cómo evitar su contagio

En el Día Mundial contra la Hepatitis, expertos indican que el consumo abusivo de alcohol y la infección por virus de hepatitis B y C son los principales peligros

Víctor Ingrassia

28 DE JULIO DE 2016


























La hepatitis es la octava causa de muerte en el mundo. Foto: Archivo / Victor Ingrassia


Silenciosa, ingresa al cuerpo humano y muchas veces, silenciosamente se va, eliminada por el propio hígado. Pero cuando esto no ocurre, el virus de la hepatitis permanece allí alojado, dañando progresivamente este vital órgano, hasta que es demasiado tarde y estamos a la espera de un trasplante milagroso o los últimos días de vida.


La hepatitis es una inflamación del hígado que puede remitir espontáneamente o evolucionar hacia una fibrosis (cicatrización), una cirrosis o un cáncer de hígado. Los virus son la causa más frecuente de las hepatitis, que también pueden deberse a otras infecciones, sustancias tóxicas (por ejemplo, el alcohol o determinadas drogas) o enfermedades autoinmunitarias.

Hoy, en el Día Mundial contra la Hepatitis, las estadísticas mundiales indican que esta enfermedad es la octava causa de muerte en el mundo, por delante de los accidentes viales, HIV o diabetes y se cobra la vida de 1,5 millones de personas cada año en todo el mundo. Se trata de un grupo de enfermedades infecciosas que comprenden las hepatitis A, B, C, D y E y pueden provocar hepatopatías agudas y crónicas.























"Las principales causas de este tipo de lesiones son el consumo abusivo de alcohol y la infección por virus de hepatitis B y C. La tipo B es considerada la octava causa de muerte en el mundo, mientras que la C es la primera causa de trasplante hepático en occidente", explicó a LA NACION el doctor Esteban Gonzalez Ballerga, de la división Gastroenterología del Hospital de Clínicas.


En la Argentina, el Ministerio de Salud de la Nación estima que cerca de 800.000 personas, el 2% de la población, se encuentran infectadas con los tipos B y C, ya que sólo unos 20.000 tienen diagnóstico y apenas 5000 están bajo tratamiento, lo que significa que la gran mayoría no sabe que tiene la enfermedad.

Esta enfermedad puede prevenirse con vacunación en los casos A y B y con nuevos tratamientos puede lograrse la cura del tipo C, que no posee vacuna. En este caso, se trata de antivirales llamados, genéricamente, de acción directa. "La clave es el diagnóstico precoz y el tratamiento oportuno, antes de llegar a una lesión severa del hígado", agregó Gonzalez Ballerga.

Cuando el tratamiento es caro y no llega


Eduardo Perez Pegué es paciente de hepatitis C y trabaja desde hace 15 años en la fundación HCV Sin Fronteras para que estén a disposición los medicamentos en forma gratuita o accesible, como ocurre en los países vecinos, para tratar su enfermedad. "Reclamamos medidas concretas y urgentes, ya que hay 800.000 argentinos con hepatitis C, progresando hacia una cirrosis o cáncer hepático, y desde el Gobierno no hay un plan de compra de medicamentos", sostiene.

Eduardo recordó la historia de Beto Fava, un paciente con hepatitis C que tras 11 años de lucha, y casi un año esperando la aprobación en la Argentina de los tratamientos que podrían haberle salvado la vida, falleció el año pasado.

A Beto y su mujer les diagnosticaron hepatitis C en 1999, durante 11 años pelearon para conseguir el tratamiento, fue necesaria una carta documento al Ministerio de Desarrollo Social en el año 2009, para que obtuviera la medicación, el virus ya había tenido tiempo para avanzar dañando su hígado con una cirrosis. Luego del tratamiento de Interferón y Ribavirina, el virus volvió a aparecer.

Un año antes de su muerte recibió la noticia esperanzadora, "¡Esta vez sí!, llegan nuevos tratamientos para su Hepatitis C", que lograrían curar su virus y el de Mercedes su compañera de siempre. Pero el pasado 7 de octubre, la hepatitis C le ganó antes que le llegara la medicación prometida: Beto falleció y su mujer Mercedes continua con la lucha, a la espera de acceder a los medicamentos que ella necesita.

























El problema del costo del tratamiento

En la Argentina existen 12 esquemas de tratamiento aprobados por la Anmat, de los cuales en el país se utiliza la combinación interferón más ribavirina, durante un año con hasta un 50% de éxito. Después, surgieron dos drogas nuevas: telaprevir y boceprevir, que, empleadas junto con interferón, llegan a una efectividad del 75%, pero con mayor toxicidad.

En los últimos tres años llegaron los fármacos de última generación que permiten curar a casi el 98% de los pacientes con hepatitis C, con tratamientos de hasta 3 meses y casi sin efectos colaterales. Se trata de los antivirales sofosbuvir, simeprevir, daclatasvir [los dos últimos, ya aprobados en el país], paritaprevir/ombitasprevir y dasabuvir/ritonavir, que se usan en distintas combinaciones.


El problema que destacan los profesionales es el alto costo de las nuevas drogas: en Estados Unidos el tratamiento asciende a los 84.000 dólares, aunque en otros países gracias a la intervención del Estado, se lograron bajar considerablemente los costos: en Brasil cuesta 7500 dólares y en Egipto 1000.

"En los últimos años, la introducción de nuevos tratamientos ha cambiado en forma radical el escenario de la hepatitis C, donde es posible su erradicación en poco tiempo. Pero hoy, el desafío ya no es la cura sino la accesibilidad a los tratamientos", explicó el doctor Ricardo Mastai, de la Unidad de Trasplante del Hospital Alemán.

"De acuerdo a un reciente estudio, los nuevos tratamientos permitieron que un tercio de quienes padecían enfermedad hepática avanzada y necesitaban un trasplante tuvieran una mejoría clínica que permitió retirarlos de la lista de espera", reveló el doctor Adrián Gadano, presidente de la Asociación Argentina para el Estudio de las Enfermedades del Hígado , A.A.E.E.H, en relación a un estudio publicado por la revista científica Journal of Hepatology en el que se investigaron en Europa grupos de pacientes afectados por la Hepatitis C a la espera de un trasplante.

Según el Instituto Nacional Central Único Coordinador de Ablación e Implante (Incucai), en Argentina unos 1200 están en lista de espera para un trasplante de hígado. De esos 1200 casos, unos 300 corresponden a infectados por Hepatitis C.












































Síntomas

Aproximadamente el 70 a 80% de las personas con infección aguda por VHC no presentan ningún síntoma. Las personas con infección crónica por el virus de la Hepatitis C pueden tener síntomas no específicos, que van desde leves hasta severos, tales como: fatiga, naúseas, pértida de apetito, cefaléa, dolor abdominal y síntomas similares a la gripe.

Tipos y cuidados


La hepatitis A: se transmite a través del agua o de alimentos contaminados con el virus. La falta de servicios sanitarios adecuados y de higiene de manos en la manipulación de alimentos, incrementa el riesgo de transmisión del virus tipo A. Suele aparecer también después de las inundaciones

La hepatitis B: es una de las principales causas de hepatitis aguda en adultos, pudiendo evolucionar en cirrosis o cáncer primario de hígado en sus formas crónicas. Es importante destacar que, tanto la infección aguda como la crónica suelen ser asintomáticas. Esta hepatitis puede transmitirse por prácticas sexuales no seguras, por exposición a sangre infectada y de madres a recién nacidos

La hepatitis C: es la principal causa de cirrosis, cáncer primario de hígado y trasplante hepático en nuestro país, estimándose en casi 400.000 la cantidad de personas afectadas y de la cual, solo 1/3 conoce su diagnóstico. Se recomienda realizar el test para hepatitis C, al menos una vez en la vida, fundamentalmente en nacidos entre 1945 y 1972, pacientes con alteraciones de en los análisis de sangre relacionados al hígado, expuestos a inyecciones no seguras, transfusiones antes de 1995, hemodiálisis, portadores de HIV o hepatitis B y personas que lleven a cabo prácticas sexuales no seguras.

El estudio consiste en un simple análisis de sangre y los tratamientos actuales son altamente seguros y eficaces. También es recomendable hacerse el análisis en aquellos casos en los que la madre le pudo haber transmitido el virus al hijo, o donde se compartió elementos personales como afeitadoras o cepillos de dientes con una persona infectada, se realizó piercing o se utilizó agujas de tatuajes no debidamente esterilizadas o se realizaron procedimientos médicos u odontológicos con materiales inadecuadamente tratados o no esterilizados.

Según datos de la OMS, esta enfermedad infecciosa que afecta principalmente al hígado y es causada por el virus de la hepatitis C, la padecen más de 160 millones de personas en todo el mundo (cinco veces más que el HIV), con casi tres millones de nuevos de contagios cada año.

Los médicos explican que el virus de la hepatitis C es muy particular dentro de las llamadas enfermedades del hígado, además de ser el primer causante de trasplante hepático: entre el 20 % de quienes lo contraen lo eliminan naturalmente. En el restante 80% el virus se cronifica silenciosamente a lo largo de 20 o 30 años, pasando de una fibrosis hasta cirrosis o cáncer de hígado. También en muchos casos la enfermedad es leve y no progresiva.

HepaRed, el conjunto de ONGs, activistas y grupos de pares conformados por personas que trabajan sobre la temática de las hepatitis virales crónicas, firmaron a fin del año pasado la Declaración HepaRed Argentina 2015 para llevar adelante acciones para un mayor control de las hepatitis virales y para la defensa de los derechos de las personas con Hepatitis B y/o Hepatitis C.

Campañas y atención al paciente

- La Asociación Argentina para el Estudio de las Enfermedades del Hígado comenzó su campaña "Hepatitis C: Detectar para Curar" para generar conciencia sobre la importancia de realizarse el test de la Hepatitis C, al menos una vez en la vida. Acceder al hashtag #haceteltest o bien a través de la cuenta de Twitter @AAEEH5 o del Facebook de la entidad.

- La sección Hepatología del Servicio de Gastroenterología del Hospital Británico, realizará hoy en la Sede Central de la Institución (Perdriel 74, CABA), Salón Ravenscroft, las siguientes actividades de concientización para la detección, prevención y manejo de las hepatitis virales

.9.30hs "Hepatitis virales: ¿qué debemos saber? Orientada al personal de enfermería

.11hs. "Hepatitis virales: ¿qué debemos saber?" Orientada a público general

.12.30hs "Hepatitis B y C en la Argentina de hoy, cuál es nuestro rol?" Orientada a médicos.

- Hospital Dr. Carlos Bonorino Udaondo: Av. Caseros 2061 CABA - Tel. 4306-4641 al 49 int 263. Se atenderá a libre demanda consultas de primera vez sobre hepatitis y pedidos de serología

- Universidad Maimónides: Hidalgo 775, Ciudad de Bs. As. Tel. 4905-1162 . Martes 02 de agosto de 2016 - 15hs a 18:30hs

- Hospital Nacional Prof. Alejandro Posadas:Av. Pres. Arturo U. Illia s/n y Marconi, El Palomar. Tel. (011) 4469-9300 . Hoy y mañana, de 9 a 12, en el sector 1º F. Campaña de detección de hepatitis virales y posterior atención clínica y tratamiento de las personas en quienes se detecte algún resultado anormal.













Fuente: www.lanacion.com.ar








































































































ECON/GralInt-Hunting for Gazelles/Middle management in gazelle organizations/Are Small Businesses the Biggest Producers of Jobs?

The following information is used for educational purposes only.




Hunting for Gazelles


Joshua Zumbrun

30/10/2009


Part of the reason for gloomy talk of a jobless recovery is that small businesses–the greatest generator of new jobs, says conventional wisdom–have taken a pounding. In the recession of 2001 companies with fewer than 100 employees accounted for 19% of the 4 million jobs that disappeared. This time it’s worse. Through the fourth quarter of 2008 small firms accounted for 48% of job losses. (Since the start of the recession a total 7.8 million jobs have disappeared.) Such outfits may have a tougher time recovering, since no loan officer in his right mind would return their calls.

Suppose conventional wisdom is wrong?

The idea that small businesses create most new employment derives from The Job Generation Process (1979) by economist David Birch. In 1994, however, Birch revised his thesis, isolating job-creating companies he called “gazelles.” Characterized less by size than by rapid expansion, Birch defined the species as enterprises whose sales doubled every four years. By his estimates, these firms, roughly 4% of all U.S. companies, were responsible for 70% of all new jobs. The gazelles beat out the elephants (like Wal-Mart ) and the mice (corner barbershops).

Unsurprisingly, gazelles are rare creatures. A 2008 study by Zoltan Acs, director of the Center for Entrepreneurship and Public Policy at George Mason University, found that a mere 2% to 3% of all companies were high-impact firms. Elephants and mice cut jobs, and the deeper they slice the higher unemployment rises. But when it comes to job creation, they are almost irrelevant.

Unlike mice and elephants, gazelles are tricky to spot. On average, high-impact firms are 25 years old, says Acs, and they’re not gazelles for life. “You find them in all industries and [they change] over time,” he says. In the 1990s a disproportionate number of gazelles were technology firms; in this decade many were in housing-related services, says Acs. “Where this is going to take off next, I don’t know,” Acs continues. But he’s sure there will be a new explosion of high-impact businesses.

Gazelles have certainly been hurt in the recession. But Acs thinks many are still growing, and believes they’ll be the first to start hiring again. Why? Because they are the economy’s most productive enterprises. High-impact firms have greater revenue per employee than other companies in all size categories and maintain that edge in times of prosperity and downturn. This recession has seen a dramatic surge in productivity (see chart in “Look Who’s Hiring Now”)–good breeding ground for tomorrow’s gazelles and a turnaround in the bleak employment picture.

One other myth to pop: that gazelles are starved of capital. While it’s true that a lot of small businesses have had trouble getting loans, “We are really overplaying the ‘Gee, credit’s not available’ story,” says William Dunkelberg, chief economist for the National Federation of Independent Business in Washington, D.C. According to the NFIB’s September survey, 33% of its members say they’re borrowing on a regular basis–about on a par with the post-1983 period, says Dunkelberg. (The Obama Administration recently announced plans to let small banks borrow–and presumably lend–at lower rates.) More strikingly, only 4% of surveyed firms cite financing as their chief problem. Their biggest gripes: poor sales (32%) and taxes (24%). “Why buy a new truck if you have nobody to deliver to?” asks Dunkelberg.

Gazelles may not be knocking on bankers’ doors much, but historically they’re good credit risks. In Acs’ study, in the four years after their growth phase, only 3% or so of the gazelle population died; the rest kept expanding or at least survived. “It’s all about confidence and overcoming uncertainties,” says Joel Naroff, president of Naroff Economic Advisors in Holland, Pa. Chief among their concerns are the potential costs of health care reform–and the lingering question of tax credits for job creation. It’s not certain that either will see resolution before the end of the year.

The lingering wreckage may create opportunities for survivors. “If someone goes out of business, you’re going to pick up some of the pieces,” says Acs. If enough gazelles see it that way, the recovery might not be so jobless after all.










Source:http://www.forbes.com/forbes/2009/1116/careers-small-businesses-unemployment-hunting-for-gazelles.html































Middle management in gazelle organizations

March 29th, 2015

by Bob Morris


While completing the process of evaluating workshops and seminars I conducted in 2014, I have also been scheduling and conducting additional ones in 2015. Most of my involvement is with gazelles, a majority of them companies in which venture capital firms have made a substantial investment. In that event, the VC firms are my clients and companies in their portfolios are either gazelles or potential gazelles.

As you may know already, the term “gazelle” was coined by the economist David Birch. His identification of gazelle companies followed from his 1979 report titled “The Job Generation Process” (MIT Program on Neighborhood and Regional Change), wherein he identified small companies as the biggest creators of new jobs in the economy.

In 1994, however, Birch revised his thesis, isolating job-creating companies he called “gazelles.” Characterized less by size than by rapid expansion, Birch defined the species as enterprises whose sales doubled every four years. By his estimates, these firms, roughly 4% of all U.S. companies, were responsible for 70% of all new jobs. The gazelles beat out the elephants (like Walmart) and the mice (corner barbershops). When you hear politicians say, “Small businesses create most of the new jobs,” they’re really talking about young and growing firms. They are talking about gazelles.

These are among the challenges that the leaders in a gazelle company now face:

1. How to manage rapid growth
2. How to retain the given company’s structural integrity (i.e. flawless operations)
3. How to make sound business decisions faster, especially when faced with an unexpected development
4. How to increase the capabilities of direct reports who must grow as their company grows
5. Meanwhile, how to avoid organizational burnout of people, systems, cash…enthusiasm.

Middle managers bear the brunt of coping with these challenges. They are seldom in the C-Suite, spending most of their time in the proverbial “tenches,” getting “dirt under their nails, “going the extra mile,” etc.

It is impossible to exaggerate the importance of middle managers in gazelle organizations. They must both lead and follow effectively at all levels and in all areas. If your organization needs assistance with accelerating the development of middle managers, please contact me.

Tags: "The Job Generation Process", How to avoid organizational burnout of people [comma] systems [comma] cash [comma] enthusiasm, How to increase the capabilities of direct reports who must grow as their company grows, How to make sound business decisions faster [comma] especially when faced with an unexpected development, How to manage rapid growth, How to retain the given company's structural integrity, Middle management in gazelle organizations, MIT Program on Neighborhood and Regional Change, the term “gazelle” was coined by the economist David Birch












Source: http://bobmorris.biz/middle-management-in-gazelle-organizations






Are Small Businesses the Biggest Producers of Jobs?


Kevin L. Kliesen , Julia S. Maues


It is often claimed that small firms are responsible for a disproportionately large share of new jobs that are created in the U.S. economy. If true, this speaks well of the entrepreneurial spirit of the U.S. economy, whereby newcomers introduce new ideas or production processes that lead to new and improved products or services. The rise of global companies like Wal-Mart, Microsoft and Google from small beginnings is a testament to the importance of small businesses and the economic forces they sometimes unleash. However, the claim that small businesses generate a large percentage of new jobs must be evaluated carefully. First, there isn't a universal agreement on the definition of a small business. Furthermore, the failure rates of small business are quite high. According to the Bureau of Labor Statistics, only about half of the businesses that opened in 1994 were still operating five years later. Thus, when one accounts for job destruction, small businesses appear to account for a significantly smaller share of net new jobs created in the private sector than many people might believe.

What Do Past Studies Reveal?

The importance of small businesses to job creation has been part of the economic policy narrative for some time. In 1979, then-Massachusetts Institute of Technology Professor David Birch claimed that firms with 20 or fewer employees accounted for two-thirds of all new jobs created between 1969 and 1976; firms with 100 or fewer employees accounted for 82 percent of all new jobs created. Conversely, he found that large firms (500 or more employees) accounted for only 15 percent of net job growth. Birch's finding challenged the conventional wisdom about job creation at the time and, accordingly, had enormous influence on policymakers and researchers.1

Some economists soon began to challenge Birch's findings. Using the same data as Birch, Catherine Armington and Marjorie Odle found in 1982 that businesses with 100 or fewer employees accounted for only 39 percent of net new jobs. Several years later, Charles Brown, James Hamilton and James Meddoff pointed out that 40 percent of jobs created in small businesses in 1980 no longer existed in 1986. A more up-to-date assessment of the job-creation characteristic of small businesses can be found in work published by Stephen Davis, John Haltiwanger and Scott Schuh in 1996.

These authors noted that "a common confusion between net and gross job creation distorts the overall job creation picture and hides the enormous number of new jobs created by large employers."2 The authors found that although gross job creation is high for smaller firms (100 or fewer employees), so is job destruction. Slowly, researchers were coming to the conclusion that small businesses did create a lot of new jobs, but the high failure rate of these businesses suggested that their net job creation was much lower.

Earlier this year, a study designed to look at the entire economy was published.3 The researchers found that small firms create more net jobs than do large firms, which is consistent with the conventional wisdom but generally not the thrust of past research. However, they concede that Birch overestimated the importance of small business in job creation and found that there is a much smaller difference between the net number of new jobs created by large firms and small firms than Birch originally suggested.

Business Employment Dynamics

Researchers who want to assess the claim that small businesses account for a disproportionate percentage of new jobs must first confront several issues. First, what is the best data source for the hypothesis to be tested? Second, how should a small business be defined? (The Small Business Administration says a business is small if it employs fewer than 500 people. However, it may not be wise to lump together a Silicon Valley startup with a relatively large, established manufacturer.) Third, should the focus be on the gross number of jobs created or the net number of jobs created? The research suggests the latter. Why? Because even during the depths of the 2007-09 recession, businesses were still adding an average of nearly 800,000 new jobs a month. But they were shedding an even larger number of jobs per month—about 971,000.

In this article, we use the Business Employment Dynamics (BED) dataset from the Bureau of Labor Statistics.4 One drawback of the BED is that it has less than 20 years of history, which may limit the ability to draw firm conclusions. The analysis in this article uses the following breakdown of firm size: 1-19 employees; 20-99 employees; 100-499 employees; and 500 or more employees.

Job Gains by Firm Size

The table shows average gross and net job gains at all private business establishments from the third quarter of 1992 through the first quarter of 2010.5 Over this roughly 18-year period, gross job gains per quarter averaged a little less than 2.8 million, or about 929,000 per month. Since the 2007-2009 recession was extremely severe, the table includes a separate column that excludes the data from that period. The lower half of the table shows that businesses with fewer than 20 employees provided the largest percentage of gross job gains (about 30 percent). Businesses with between 20 and 99 employees accounted for the next largest share (about 27 percent), with the largest firms (500 or more) accounting for a somewhat smaller percentage (about 26 percent). The remaining category—businesses with between 100 and 499 employees—accounted for a smaller percentage of gross job gains. All of these percentages are little-changed if we exclude the recession period.


Gross and Net Job Gains by Firm Size

Average job gains (in thousands) per quarter, 1992:Q3 to 2010:Q1

Gross Job Gains
Net Job Gains
Size
Total Sample Period
Excluding 2007-09 Recession

Total Sample Period
Excluding 2007-09 Recession
1 to 19
821
828

16
28
20 to 99
747
758

25
40
100 to 499
496
505

25
37
500 or more
722
739

40
68
TOTAL
2,787
2,831

105
173

Percent of Total
1 to 19
29.5%
29.3%

15.0%
16.1%
20 to 99
26.8%
26.8%

23.6%
23.1%
100 to 499
17.8%
17.8%

23.4%
21.3%
500 or more
25.9%
26.1%

37.9%
39.4%
TOTAL
100.0%
100.0%

100.0%
100.0%


SOURCE: Authors' calculations based on Bureau of Labor Statistics' Business Employment Dynamics dataset. Some percentages do not total 100 due to rounding.




The analysis in the table seems consistent with the conventional wisdom that small businesses are the largest source of job creation in the economy. However, as suggested by previous studies, the conclusion tends to change when the focus switches to net job creation.

The two right-hand columns in the table examine net job gains. Net job gains are defined as job gains minus job losses. Three findings are apparent from the table. First, net job gains were significantly smaller than gross job gains. The net gains per quarter averaged only 105,000, or 35,000 per month. Second, the table shows that the recession dramatically reduced the rate of net job creation. Once net job losses during the recession are removed from the calculation, the number of net jobs rose to 173,000 per quarter (about 58,000 per month). Finally, and perhaps most importantly, the BED data show that since 1992, net job creation tended to be largest among the largest firms: These firms accounted for about 38 percent of the total. The smallest firms showed the smallest percentage of net jobs created. This result does not change if the past recession is excluded from the sample.

In short, small businesses showed higher rates of gross job creation, but they also exhibited high rates of job destruction. Looked at from this standpoint, net job creation matters most.

Linpeng Zheng provided research assistance.

Endnotes

Birch followed up his original study with several subsequent studies (not cited herein). [back to text]
One drawback of this study is that it focused on the manufacturing sector, which is a relatively small share of the economy and, thus, probably not a good representation of total job creation. [back to text]
See Neumark, Wall and Zhang. [back to text]
The BED is a quarterly series that is based on the Quarterly Census of Employment and Wages, which uses state unemployment insurance records. See Spletzer et al. for more information about the BED. [back to text]
Changes in employment can arise from opening or expanding businesses, or closing or contracting businesses. Gross job gains include the sum of all jobs added at both opening and at expanding establishments. Gross job losses, then, include the sum of all jobs lost at both closing establishments or contracting establishments. [back to text]

References

Armington, Catherine; and Odle, Marjorie. "Small Business: How Many Jobs?" The Brookings Review, Winter 1982, Vol. 1, No. 2, pp. 14-17.

Birch, David L. The Job Generation Process. Cambridge, Mass.: MIT Program on Neighborhood and Regional Change, 1979.

Brown, Charles; Hamilton, James; and Medoff, James. Employers Large and Small. Cambridge, Mass.: Harvard University Press, 1990.

Davis, Stephen J.; Haltiwanger, John C.; and Schuh, Scott. Job Creation and Destruction. Cambridge, Mass.: MIT Press, 1996.

Haltiwanger, John .C.; Jarmin, Ron C.; and Miranda, Javier. "Who Creates Jobs? Small vs. Large vs. Young." NBER Working Paper 16300, August 2010. See www.nber.org/papers/w16300

Neumark, David; Wall, Brandon; and Zhang, Junfu. "Do Small Businesses Create More Jobs? New Evidence for the United States from the National Establishment Time Series." The Review of Economics and Statistics, February 2011, Vol. 93, No. 1, pp. 16-29.

Spletzer, James R.; Faberman, R. Jason; Sadeghi, Akbar; Talan, David M.; and Clayton, Richard L. "Business Employment Dynamics: New Data on Gross Job Gains and Losses." Monthly Labor Review, April 2004, pp. 29-42.







Source: https://www.stlouisfed.org/publications/regional-economist/april-2011/are-small-businesses-the-biggest-producers-of-jobs

Tuesday, July 26, 2016

GralInt-Water.org: Three Mothers, Three Stories (Narrated by Jodie Foster)

The following information is used for educational purposes only.





Three Mothers, Three Stories (Narrated by Jodie Foster)



Water.org

Published on May 7, 2013


Honor your mother with an e-card and a life-changing donation: http://water.org/moms/

The dignity and strength of women around the world is astounding - in celebration of Mother's Day, watch the inspiring stories of three mothers who broke the cycle of poverty, and found a path to water.




























Source: www.youtube.com

Sunday, July 24, 2016

BRAIN/GralInt-TED Talks-Make your brain smarter: it's not what you think: Sandra Chapman, Ph.D. at TEDxRockCreekPark

The following information is used for educational purposes only.






Make your brain smarter: it's not what you think: Sandra Chapman, Ph.D. at TEDxRockCreekPark


Published on May 15, 2013


Sandra Bond Chapman, PhD, founder and leader of the Center for BrainHealth at UT Dallas relates new scientific evidence that you literally can think your brain smarter and healthier. She debunks long-standing beliefs about what smart is and shares proven strategies to expand your brain span to more closely match the ever-increasing human lifespan. Whether you are young or old, Dr. Chapman will inspire you to test the limits of your own brain potential.
Your brain is your greatest asset and natural resource. It is the most changeable part of your entire body. However, vastly more personal attention and effort are directed at improving physical health than at strengthening and regaining the highest level of brain performance. Dr. Chapman's research taps into the secret of making your brain smarter, harnessing the CEO of your brain performance - your frontal lobes. Her techniques show how to engage your frontal lobes, ignite your passion and learn to be strategic about the way you expend precious brain energy.
From teens to corporate executives to warriors to healthy agers, as well as individuals with brain disease or injury, Dr. Chapman and her team at the Center for BrainHealth have created strategies to increase creativity, energy and focus for people of all ages. In the junior high school classroom, these strategies take a new approach to education and have improved teen reasoning ability, showing 30% gains in critical thinking across socioeconomic status. Business leaders who have embraced these healthy brain habits report increased innovation and their employees demonstrate greater productivity and efficiency. Former military service personnel have used these brain-training techniques to bridge barriers to returning to civilian society, making home life and work life markedly better. One veteran described his transformational experience as "cognitive resurrection". Healthy agers and individuals debilitated by mild cognitive impairment, which is often the pre-cursor to Alzheimer's disease, showed increases in memory and other cognitive functions. Individuals with concussions or traumatic brain injury (TBI) exhibited brain repair and improved cognitive performance, even years after injury.
Dr. Chapman's dream is that you will act now to make an investment in your brain potential and build the cognitive reserves today to ensure that your best brain years are ahead of you, not behind you.

In the spirit of ideas worth spreading, TEDx is a program of local, self-organized events that bring people together to share a TED-like experience. At a TEDx event, TEDTalks video and live speakers combine to spark deep discussion and connection in a small group. These local, self-organized events are branded TEDx, where x = independently organized TED event. The TED Conference provides general guidance for the TEDx program, but individual TEDx events are self-organized.* (*Subject to certain rules and regulations)
























GralInt-TED Talks-Change anything! Use skillpower over willpower: Al Switzler at TEDxFremont

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Change anything! Use skillpower over willpower: Al Switzler at TEDxFremont


Published on Dec 4, 2012


How do you break down mental barriers and beat the willpower trap? Al Switzler, cofounder of VitalSmarts, researches methods for driving sustainable, measurable behavior change. Switzler is coauthor of four NYT bestsellers, including Change Anything.
http://www.alswitzler.com

About TEDx, x = independently organized event
In the spirit of ideas worth spreading, TEDx is a program of local, self-organized events that bring people together to share a TED-like experience. At a TEDx event, TEDTalks video and live speakers combine to spark deep discussion and connection in a small group. These local, self-organized events are branded TEDx, where x = independently organized TED event. The TED Conference provides general guidance for the TEDx program, but individual TEDx events are self-organized.* (*Subject to certain rules and regulations)



























GralInt-TED Talks-How to believe in yourself: Jim Cathcart at TEDxDelrayBeach

The following information is used for educational purposes only.




How to believe in yourself: Jim Cathcart at TEDxDelrayBeach



Published on Oct 17, 2013


Jim Cathcart thought he would never make a difference. An average student from a working class family with no athletic or special skills, he expected an unremarkable existence. But one radio message in 1972 changed the direction of his life & authored his belief in his potential. Today, he's a Hall of Fame Speaker, and has authored 16 books. While changing himself, Jim also discovered how to help others believe in themselves, too.

In the spirit of ideas worth spreading, TEDx is a program of local, self-organized events that bring people together to share a TED-like experience. At a TEDx event, TEDTalks video and live speakers combine to spark deep discussion and connection in a small group. These local, self-organized events are branded TEDx, where x = independently organized TED event. The TED Conference provides general guidance for the TEDx program, but individual TEDx events are self-organized.* (*Subject to certain rules and regulations)





















GralInt-TED Talks-The art of making impossible, possible: Ingrid Vanderveldt at TEDxFiDiWomen

The following information is used for educational purposes only.




The art of making impossible, possible: Ingrid Vanderveldt at TEDxFiDiWomen



Uploaded on Dec 6, 2011


Ingrid Vanderveldt (iV) is the Entrepreneur-in-Residence for Dell, CEO of Green Girl Energy, Founding Organizer of the GLASS Forum (Global Leadership & Sustainable Success), seasoned entrepreneur, business television personality and a passionate advocate for WOMEN + GREEN sustainability initiatives. Ingrid has designed and executed corporate, entrepreneurial and philanthropic programs to advance the economic success of women-owned and green-focused businesses and has worked with companies including Microsoft, Dell, Humana and SAIC. Ingrid created CNBC's first original primetime series, "American Made" reaching over 1 M viewers around the globe and has hosted the Web shows 'On the Road with iV' and the 'Road to SXSW 2010'. 2010 inspired a new mission of "Empowering a Billion Women by 2020" to help foster a more sustainable future for our planet. Ingrid serves on the Advisory Boards of SXSW Eco, World Blu, Current Motor, the Young Entrepreneur Council and Visionary Holdings. She advises and supports Richard Branson's Carbon War Room, XPRIZE, is a co-founder of The Billionaire Girls Club and is an invited member of the Dell Women's Entrepreneur Network(DWEN). She has been featured in the Wall Street Journal, USA Today, New York Times, Inc. Magazine, the Today Show and The Big Idea. iV has been awarded a technology patent and has a Master's in Architecture and an MBA in Entrepreneurship.
























GralInt-TED Talks-Speak like a leader | Simon Lancaster | TEDxVerona

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Speak like a leader | Simon Lancaster | TEDxVerona


Published on May 22, 2016


Did you know there is a secret language of leadership that determines who reaches the top in politics and business?
In this fast-paced and frequently funny TEDx talk, top speechwriter, Simon Lancaster, sets out the techniques that you can use to speak like a leader. The talk culminates in Simon Lancaster instantly improvising a powerful leadership speech based on an idea suggested by the audience.

Simon Lancaster is one of the world’s top speechwriters. He started working as a speechwriter in the late 1990s to members of Tony Blair’s Cabinet and now writes speeches for the CEOs of some of the biggest companies in the world including Unilever, Intercontinental Hotels and HSBC. He is a visiting lecturer at Cambridge University, Henley Business School and author of two best-selling books on communication: Speechwriting: The Expert Guide and Winning Minds: Secrets from the Language of Leadership. His award winning workshops on the language of leadership have been run to great acclaim around the world: for more information, see www.bespokeleadershipdevelopment.com.


















GralInt-TED Talks-Learning to be awesome at anything you do, including being a leader | Tasha Eurich | TEDxMileHigh

The following information is used for educational purposes only.






Learning to be awesome at anything you do, including being a leader | Tasha Eurich | TEDxMileHigh


Published on Jul 15, 2014

This talk was given at a local TEDx event, produced independently of the TED Conferences. Can we learn to lead, or is leadership something we're born with? In this thought-provoking talk, Tasha Eurich shares a prescription to be not just awesome at leadership, but anything else you want to improve.

With a contagious passion and energy, Tasha Eurich pairs her scientific savvy in human behavior with a practical approach to solving business challenges. Her life's work is to help companies succeed by making their leaders awesome. In 2013, Tasha released her first book "Bankable Leadership: Happy People, Bottom Line Results and the Power to Deliver Both." It debuted at #8 on the New York Times best-seller list and was named a Top 10 Small Business book by Small Business Trends in 2013.

About TEDx, x = independently organized event In the spirit of ideas worth spreading, TEDx is a program of local, self-organized events that bring people together to share a TED-like experience. At a TEDx event, TEDTalks video and live speakers combine to spark deep discussion and connection in a small group. These local, self-organized events are branded TEDx, where x = independently organized TED event. The TED Conference provides general guidance for the TEDx program, but individual TEDx events are self-organized.* (*Subject to certain rules and regulations)





















TOEIC- English Listening Practice

The following information is used for educational purposes only.







TOEIC- English Listening Practice
























Answer Key:


01A 02C 03B 04A 05B 06C 07C 08B 09B 10B
11B 12C 13A 14A 15B 16B 17C 18A 19A 20C
21B 22B 23A 24A 25B 26C 27B 28A 29B 30C
31B 32A 33A 34B 35B 36C 37A 38A 39B 40A
41C 42A 43B 44D 45C 46C 47C 48B 49B 50D
51B 52C 53C 54C 55D 56A 57C 58D 59C 60D
61B 62B 63C 64C 65D 66B 67A 68A 69B 70A
71B 72A 73B 74D 75A 76A 77C 78A 79B 80C
81B 82B 83C 84A 85B 86B 87B 88A 89C 90A
91C 92B 93C 94C 95B 96C 97D 98B 99D 100A















Source: www.youtube.com

BRAIN/GralInt-TED Talks-Ed Boyden: Baby diapers inspired this new way to study the brain

The following information is used for educational purposes only.





Filmed June 2016 at TEDSummit

Ed Boyden: Baby diapers inspired this new way to study the brain



Neuroengineer Ed Boyden wants to know how the tiny biomolecules in our brains generate emotions, thoughts and feelings — and he wants to find the molecular changes that lead to disorders like epilepsy and Alzheimer's. Rather than magnify these invisible structures with a microscope, he wondered: What if we physically enlarge them and make them easier to see? Learn how the same polymers used to make baby diapers swell could be a key to better understanding our brains.


















































Transcript:


Hello, everybody. I brought with me today a baby diaper. You'll see why in a second. Baby diapers have interesting properties. They can swell enormously when you add water to them, an experiment done by millions of kids every day.
(Laughter)
But the reason why is that they're designed in a very clever way. They're made out of a thing called a swellable material. It's a special kind of material that, when you add water, it will swell up enormously, maybe a thousand times in volume. And this is a very useful, industrial kind of polymer. But what we're trying to do in my group at MIT is to figure out if we can do something similar to the brain. Can we make it bigger, big enough that you can peer inside and see all the tiny building blocks, the biomolecules, how they're organized in three dimensions, the structure, the ground truth structure of the brain, if you will? If we could get that, maybe we could have a better understanding of how the brain is organized to yield thoughts and emotions and actions and sensations. Maybe we could try to pinpoint the exact changes in the brain that result in diseases, diseases like Alzheimer's and epilepsy and Parkinson's, for which there are few treatments, much less cures, and for which, very often, we don't know the cause or the origins and what's really causing them to occur. Now, our group at MIT is trying to take a different point of view from the way neuroscience has been done over the last hundred years. We're designers. We're inventors. We're trying to figure out how to build technologies that let us look at and repair the brain. And the reason is, the brain is incredibly, incredibly complicated.
So what we've learned over the first century of neuroscience is that the brain is a very complicated network, made out of very specialized cells called neurons with very complex geometries, and electrical currents will flow through these complexly shaped neurons. Furthermore, neurons are connected in networks. They're connected by little junctions called synapses that exchange chemicals and allow the neurons to talk to each other. The density of the brain is incredible. In a cubic millimeter of your brain, there are about 100,000 of these neurons and maybe a billion of those connections. But it's worse. So, if you could zoom in to a neuron, and, of course, this is just our artist's rendition of it. What you would see are thousands and thousands of kinds of biomolecules, little nanoscale machines organized in complex, 3D patterns, and together they mediate those electrical pulses, those chemical exchanges that allow neurons to work together to generate things like thoughts and feelings and so forth.
Now, we don't know how the neurons in the brain are organized to form networks, and we don't know how the biomolecules are organized within neurons to form these complex, organized machines. If we really want to understand this, we're going to need new technologies. But if we could get such maps, if we could look at the organization of molecules and neurons and neurons and networks, maybe we could really understand how the brain conducts information from sensory regions, mixes it with emotion and feeling, and generates our decisions and actions. Maybe we could pinpoint the exact set of molecular changes that occur in a brain disorder. And once we know how those molecules have changed, whether they've increased in number or changed in pattern, we could use those as targets for new drugs, for new ways of delivering energy into the brain in order to repair the brain computations that are afflicted in patients who suffer from brain disorders.
We've all seen lots of different technologies over the last century to try to confront this. I think we've all seen brain scans taken using MRI machines. These, of course, have the great power that they are noninvasive, they can be used on living human subjects. But also, they're spatially crude. Each of these blobs that you see, or voxels, as they're called, can contain millions and millions of neurons. So it's not at the level of resolution where it can pinpoint the molecular changes that occur or the changes in the wiring of these networks that contributes to our ability to be conscious and powerful beings.
At the other extreme, you have microscopes. Microscopes, of course, will use light to look at little tiny things. For centuries, they've been used to look at things like bacteria. For neuroscience, microscopes are actually how neurons were discovered in the first place, about 130 years ago. But light is fundamentally limited. You can't see individual molecules with a regular old microscope. You can't look at these tiny connections. So if we want to make our ability to see the brain more powerful, to get down to the ground truth structure, we're going to need to have even better technologies.
My group, a couple years ago, started thinking: Why don't we do the opposite? If it's so darn complicated to zoom in to the brain, why can't we make the brain bigger? It initially started with two grad students in my group, Fei Chen and Paul Tillberg. Now many others in my group are helping with this process. We decided to try to figure out if we could take polymers, like the stuff in the baby diaper, and install it physically within the brain. If we could do it just right, and you add water, you can potentially blow the brain up to where you could distinguish those tiny biomolecules from each other. You would see those connections and get maps of the brain. This could potentially be quite dramatic.
We brought a little demo here. We got some purified baby diaper material. It's much easier just to buy it off the Internet than to extract the few grains that actually occur in these diapers. I'm going to put just one teaspoon here of this purified polymer. And here we have some water. What we're going to do is see if this teaspoon of the baby diaper material can increase in size. You're going to see it increase in volume by about a thousandfold before your very eyes. I could pour much more of this in there, but I think you've got the idea that this is a very, very interesting molecule, and if can use it in the right way, we might be able to really zoom in on the brain in a way that you can't do with past technologies.
OK. So a little bit of chemistry now. What's going on in the baby diaper polymer? If you could zoom in, it might look something like what you see on the screen. Polymers are chains of atoms arranged in long, thin lines. The chains are very tiny, about the width of a biomolecule, and these polymers are really dense. They're separated by distances that are around the size of a biomolecule. This is very good because we could potentially move everything apart in the brain. If we add water, what will happen is, this swellable material is going to absorb the water, the polymer chains will move apart from each other, and the entire material is going to become bigger. And because these chains are so tiny and spaced by biomolecular distances, we could potentially blow up the brain and make it big enough to see.
Here's the mystery, then: How do we actually make these polymer chains inside the brain so we can move all the biomolecules apart? If we could do that, maybe we could get ground truth maps of the brain. We could look at the wiring. We can peer inside and see the molecules within. To explain this, we made some animations where we actually look at, in these artist renderings, what biomolecules might look like and how we might separate them. Step one: what we'd have to do, first of all, is attach every biomolecule, shown in brown here, to a little anchor, a little handle. We need to pull the molecules of the brain apart from each other, and to do that, we need to have a little handle that allows those polymers to bind to them and to exert their force.
Now, if you just take baby diaper polymer and dump it on the brain, obviously, it's going to sit there on top. So we need to find a way to make the polymers inside. And this is where we're really lucky. It turns out, you can get the building blocks, monomers, as they're called, and if you let them go into the brain and then trigger the chemical reactions, you can get them to form those long chains, right there inside the brain tissue. They're going to wind their way around biomolecules and between biomolecules, forming those complex webs that will allow you, eventually, to pull apart the molecules from each other. And every time one of those little handles is around, the polymer will bind to the handle, and that's exactly what we need in order to pull the molecules apart from each other.
All right, the moment of truth. We have to treat this specimen with a chemical to kind of loosen up all the molecules from each other, and then, when we add water, that swellable material is going to start absorbing the water, the polymer chains will move apart, but now, the biomolecules will come along for the ride. And much like drawing a picture on a balloon, and then you blow up the balloon, the image is the same, but the ink particles have moved away from each other. And that's what we've been able to do now, but in three dimensions.
There's one last trick. As you can see here, we've color-coded all the biomolecules brown. That's because they all kind of look the same. Biomolecules are made out of the same atoms, but just in different orders. So we need one last thing in order to make them visible. We have to bring in little tags, with glowing dyes that will distinguish them. So one kind of biomolecule might get a blue color. Another kind of biomolecule might get a red color. And so forth. And that's the final step. Now we can look at something like a brain and look at the individual molecules, because we've moved them far apart enough from each other that we can tell them apart.
So the hope here is that we can make the invisible visible. We can turn things that might seem small and obscure and blow them up until they're like constellations of information about life. Here's an actual video of what it might look like. We have here a little brain in a dish -- a little piece of a brain, actually. We've infused the polymer in, and now we're adding water. What you'll see is that, right before your eyes -- this video is sped up about sixtyfold -- this little piece of brain tissue is going to grow. It can increase by a hundredfold or even more in volume. And the cool part is, because those polymers are so tiny, we're separating biomolecules evenly from each other. It's a smooth expansion. We're not losing the configuration of the information. We're just making it easier to see.
So now we can take actual brain circuitry -- here's a piece of the brain involved with, for example, memory -- and we can zoom in. We can start to actually look at how circuits are configured. Maybe someday we could read out a memory. Maybe we could actually look at how circuits are configured to process emotions, how the actual wiring of our brain is organized in order to make us who we are. And of course, we can pinpoint, hopefully, the actual problems in the brain at a molecular level. What if we could actually look into cells in the brain and figure out, wow, here are the 17 molecules that have altered in this brain tissue that has been undergoing epilepsy or changing in Parkinson's disease or otherwise being altered? If we get that systematic list of things that are going wrong, those become our therapeutic targets. We can build drugs that bind those. We can maybe aim energy at different parts of the brain in order to help people with Parkinson's or epilepsy or other conditions that affect over a billion people around the world.
Now, something interesting has been happening. It turns out that throughout biomedicine, there are other problems that expansion might help with. This is an actual biopsy from a human breast cancer patient. It turns out that if you look at cancers, if you look at the immune system, if you look at aging, if you look at development -- all these processes are involving large-scale biological systems. But of course, the problems begin with those little nanoscale molecules, the machines that make the cells and the organs in our body tick. So what we're trying to do now is to figure out if we can actually use this technology to map the building blocks of life in a wide variety of diseases. Can we actually pinpoint the molecular changes in a tumor so that we can actually go after it in a smart way and deliver drugs that might wipe out exactly the cells that we want to?
You know, a lot of medicine is very high risk. Sometimes, it's even guesswork. My hope is we can actually turn what might be a high-risk moon shot into something that's more reliable. If you think about the original moon shot, where they actually landed on the moon, it was based on solid science. We understood gravity; we understood aerodynamics. We knew how to build rockets. The science risk was under control. It was still a great, great feat of engineering. But in medicine, we don't necessarily have all the laws. Do we have all the laws that are analogous to gravity, that are analogous to aerodynamics? I would argue that with technologies like the kinds I'm talking about today, maybe we can actually derive those. We can map the patterns that occur in living systems, and figure out how to overcome the diseases that plague us.
You know, my wife and I have two young kids, and one of my hopes as a bioengineer is to make life better for them than it currently is for us. And my hope is, if we can turn biology and medicine from these high-risk endeavors that are governed by chance and luck, and make them things that we win by skill and hard work, then that would be a great advance.
Thank you very much.
(Applause)


ChatGPT, una introducción realista, por Ariel Torres

The following information is used for educational purposes only.           ChatGPT, una introducción realista    ChatGPT parece haber alcanz...