The following information is used for educational purposes only.
Transcript:
Everything is covered in invisible ecosystemsmade of tiny lifeforms: bacteria, viruses and fungi.Our desks, our computers, our pencils, our buildingsall harbor resident microbial landscapes.As we design these things, we could be thinkingabout designing these invisible worlds,and also thinking about how they interactwith our personal ecosystems.
Our bodies are home to trillions of microbes,and these creatures define who we are.The microbes in your gut can influence your weight and your moods.The microbes on your skin can help boost your immune system.The microbes in your mouth can freshen your breath,or not,and the key thing is that our personal ecosystemsinteract with ecosystems on everything we touch.So, for example, when you touch a pencil,microbial exchange happens.
If we can design the invisible ecosystems in our surroundings,this opens a path to influencingour health in unprecedented ways.
I get asked all of the time from people,"Is it possible to really design microbial ecosystems?"And I believe the answer is yes.I think we're doing it right now,but we're doing it unconsciously.I'm going to share data with youfrom one aspect of my research focused on architecturethat demonstrates how, through both consciousand unconscious design,we're impacting these invisible worlds.
This is the Lillis Business Complex at the University of Oregon,and I worked with a team of architects and biologiststo sample over 300 rooms in this building.We wanted to get something like a fossil record of the building,and to do this, we sampled dust.From the dust, we pulled out bacterial cells,broke them open, and compared their gene sequences.This means that people in my groupwere doing a lot of vacuuming during this project.This is a picture of Tim, who,right when I snapped this picture, reminded me,he said, "Jessica, the last lab group I worked inI was doing fieldwork in the Costa Rican rainforest,and things have changed dramatically for me."
So I'm going to show you now first what we found in the offices,and we're going to look at the data through a visualization toolthat I've been working on in partnership with Autodesk.The way that you look at this data is,first, look around the outside of the circle.You'll see broad bacterial groups,and if you look at the shape of this pink lobe,it tells you something about the relative abundance of each group.So at 12 o'clock, you'll see that offices have a lot ofalphaproteobacteria, and at one o'clockyou'll see that bacilli are relatively rare.
Let's take a look at what's going on in different space types in this building.If you look inside the restrooms,they all have really similar ecosystems,and if you were to look inside the classrooms,those also have similar ecosystems.But if you look across these space types,you can see that they're fundamentally differentfrom one another.I like to think of bathrooms like a tropical rainforest.I told Tim, "If you could just see the microbes,it's kind of like being in Costa Rica. Kind of."And I also like to think of offices as being a temperate grassland.
This perspective is a really powerful one for designers,because you can bring on principles of ecology,and a really important principle of ecology is dispersal,the way organisms move around.We know that microbes are dispersed around by peopleand by air.So the very first thing we wanted to do in this buildingwas look at the air system.Mechanical engineers design air handling unitsto make sure that people are comfortable,that the air flow and temperature is just right.They do this using principles of physics and chemistry,but they could also be using biology.If you look at the microbesin one of the air handling units in this building,you'll see that they're all very similar to one another.And if you compare this to the microbesin a different air handling unit,you'll see that they're fundamentally different.The rooms in this building are like islands in an archipelago,and what that means is that mechanical engineersare like eco-engineers, and they have the abilityto structure biomes in this building the way that they want to.
Another facet of how microbes get around is by people,and designers often cluster rooms togetherto facilitate interactions among people,or the sharing of ideas, like in labs and in offices.Given that microbes travel around with people,you might expect to see rooms that are close togetherhave really similar biomes.And that is exactly what we found.If you look at classrooms right adjacent to one another,they have very similar ecosystems,but if you go to an officethat is a farther walking distance away,the ecosystem is fundamentally different.And when I see the power that dispersal hason these biogeographic patterns,it makes me think that it's possibleto tackle really challenging problems,like hospital-acquired infections.I believe this has got to be, in part,a building ecology problem.
All right, I'm going to tell you one more story about this building.I am collaborating with Charlie Brown.He's an architect,and Charlie is deeply concerned about global climate change.He's dedicated his life to sustainable design.When he met me and realized that it was possible for himto study in a quantitative wayhow his design choices impactedthe ecology and biology of this building,he got really excited, because it added a new dimension to what he did.He went from thinking just about energyto also starting to think about human health.He helped design some of the air handling systemsin this building and the way it was ventilated.
So what I'm first going to show you isair that we sampled outside of the building.What you're looking at is a signature of bacterial communitiesin the outdoor air, and how they vary over time.Next I'm going to show you what happenedwhen we experimentally manipulated classrooms.We blocked them off at nightso that they got no ventilation.A lot of buildings are operated this way,probably where you work,and companies do this to save money on their energy bill.What we found is that these rooms remained relatively stagnantuntil Saturday, when we opened the vents up again.When you walked into those rooms,they smelled really bad,and our data suggests that it had something to do withleaving behind the airborne bacterial soupfrom people the day before.Contrast this to roomsthat were designed using a sustainable passive design strategywhere air came in from the outside through louvers.In these rooms, the air tracked the outdoor air relatively well,and when Charlie saw this, he got really excited.He felt like he had made a good choicewith the design processbecause it was both energy efficientand it washed away the building's resident microbial landscape.
The examples that I just gave you are about architecture,but they're relevant to the design of anything.Imagine designing with the kinds of microbes that we wantin a planeor on a phone.
There's a new microbe, I just discovered it.It's called BLIS, and it's been shownto both ward off pathogensand give you good breath.Wouldn't it be awesome if we all had BLIS on our phones?
A conscious approach to design,I'm calling it bioinformed design,and I think it's possible.
Thank you.
(Applause)
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